Lactic Acid – Vaginal EubiosisEthix Industries
Vaginal Eubiosis and Dysbiosis
- Vaginal Eubiosis is characterised by beneficial lactobacillus-dominated microbiota
- vaginal Dysbiosis (e.g. bacterial vaginosis, BV), characterised by an overgrowth of multiple anaerobes, is associated with an increased risk of adverse urogenital and reproductive health
- Recent studies demonstrate that lactic acid is a major antimicrobial, antiviral and exerts immunomodulatory properties.
- Lactobacilli are genus of Gram-positive, facultative anaerobic or microaerophilic, rod-shaped, non-spore-forming bacteria.( they convert sugars to lactic acid).
- Lactobacilli species are normally a major part of the vaginal microbiota. Lactobacilli forms biofilms in the vaginal microbiota, a mutualistic relationship with the human body as it protects the host against potential invasions by pathogens, and prevents vaginal infections.
- Lactic acid is active against bacterial STIs.
- Lactic acid, inactivates Chlamydia trachomati sand Neisseria gonorrhoeae as well as Escherichia coli in vitro .
- Lactic acid, targets the growthof bacteria in living , as demonstrated by inhibition of gonorrhoeae and Gardnerella vaginalis,
- These in vitro and ex vivo studies suggest that lactic acid has the potentialto maintain vaginal eubiosis or to reverse dysbiosis and protect against bacterial infctions.
- Ref: Science Direct. Gilda Tachedjian, Muriel Aldunate, Catronia S. Bradshaw, Richard A. Cone Pages 782-792
- Elisa Margolis, David N. Fredricks, in Molecular Medical Microbiology (Second Edition), 2015